Sishu Fertility Clinic



Unfortunately, the reality of the “biological clock” is not just a myth—it’s a genuine concern. As time goes by, age can turn into a formidable adversary when it comes to fertility. With more and more people choosing to delay parenthood, the ticking of the biological clock grows louder. Especially for women, once they hit the age of 30, the odds of facing infertility start to rise. But here’s the silver lining: by unraveling the inner workings of this biological clock, we can empower individuals and couples to make enlightened decisions. Armed with this knowledge, they can have meaningful conversations about the perfect timing to start a family and when to seek help if conception hurdles arise. Let’s take charge of our reproductive destiny!


The vitality of a woman’s eggs plays a crucial role in the pursuit of conception. Once a woman reaches the age of 35, both the quality and quantity of her eggs typically start diminishing gradually. This decline becomes more accelerated after the age of 40. As the quality of female eggs diminishes, the process of conceiving becomes increasingly challenging.


  • Typically, in the case of women in their thirties, approximately 12% of their eggs possess the potential to develop into babies.
  • By the time a woman reaches the age of forty, only 40% of the “good eggs” that she had originally remained.
  • The likelihood of experiencing a miscarriage increases significantly as women age. While women in their twenties have a miscarriage rate of less than 10%, it can rise to as high as 90% for women aged 45 and above.
  • The probability of miscarriage escalates from under 10% for women in their twenties to a staggering 90% for women who are 45 years old or older.
  • The period between the ages of 25 and 35 is considered the most advantageous timeframe for achieving a healthy pregnancy and childbirth.

As women grow older, the quantity of their eggs diminishes steadily. Every month, regardless of whether they are using contraception or pregnant, they lose hundreds of eggs.


  • Women who are younger than 35 should consider seeking an assessment after one year of attempting to conceive (TTC).
  • For women between the ages of 35 and 39, it is advisable to undergo an evaluation after six months of attempting to conceive (TTC).
  • Women who are 40 years of age or older are encouraged to seek consultation at the earliest opportunity.


By the time a woman is 40 years old, the chances of becoming pregnant are greatly reduced because of the fewer number of eggs available. Also, the quality of the eggs declines with time. The reduction in quality reduces the chance for normal fertilization and increases the chance of miscarriage and chromosomal defect in an embryo. 


Each patient has his or her own personal journey. Every fertility case has its own challenges. The treatment protocol for one person is often very different than that of another patient, even if they are the same age.

From diagnosis to treatment, we utilize personalized tests and treatments to help our patients make smart choices and achieve positive outcomes.

Here’s a small sampling of what tests and technologies we will utilize to help you achieve your dream of parenthood:


Through our initial Day 3 laboratory testing, we assess egg quantity by analyzing hormonal levels in the blood and conducting a standard ultrasound. Measurements of Follicle Stimulating Hormone (FSH), anti-Mullerian Hormone (AMH), and ultrasound provide an accurate evaluation of your ovarian reserve and the supply of eggs available.


As a woman’s egg quality declines, there is an increased likelihood of encountering chromosomal abnormalities in embryos. This risk becomes particularly high for women in their late 30s and beyond, given the quality of the remaining eggs in their ovarian reserve. Although it’s not possible to assess egg quality beforehand, age serves as a reliable indicator. 

By incorporating genetic testing alongside in vitro fertilization (IVF) before implanting the embryo, we can anticipate its quality and select chromosomally-normal embryos for implantation. IVF with preimplantation genetic screening (PGS) aids in the identification of embryos with the highest potential for success, leading to improved rates of live births. 

This technology is especially valuable for women of advanced age or those who have experienced previous miscarriages.