The success rate of Intrauterine Insemination (IUI) varies depending on several factors, including the age of the woman, the underlying cause of infertility, whether fertility medications are used, and the number of IUI cycles attempted.
What is the success rate of IUI treatment?
The chance of pregnancy with a single IUI cycle is between 10% to 20%. However, undergoing multiple cycles can increase the cumulative success rate of IUI to 30-60% over three to six attempts.
These are general estimates, and individual experiences may differ. Factors like age, underlying fertility issues, and the use of fertility medications can significantly impact outcomes.
Let us understand how different factors impact the intrauterine insemination success rate.
How does age Impact IUI Success Rates?
IUI success rate by age
Under 35 Years:
Women under 35 years of age tend to have higher success rates with IUI, often around 15% to 20% per cycle. Younger women tend to have higher-quality eggs with greater potential for fertilization.
Ages 35-40
The success rate decreases slightly for women aged 35 to 40, typically around 10% to 15% per cycle. The quantity of eggs also decreases with age, leading to fewer opportunities for fertilization.
Over 40 Years
Women over 40 have lower success rates, usually less than 10% per cycle, due to egg quality and quantity.
How does the cause of Infertility impact the IUI success rate?
Unexplained Infertility
Couples with unexplained infertility often have success rates on the higher end of the spectrum, as IUI can be particularly effective when no specific cause of infertility is identified.
Mild Male Factor Infertility
Suppose the male partner has a mild sperm abnormality (such as low sperm count or motility). In that case, IUI can improve the chances of pregnancy by concentrating and directly placing sperm in the uterus. Success rates can vary from 5% to 15% per cycle, depending on the severity.
Cervical Factor Infertility
IUI is beneficial in cases where the cervical mucus is hostile to sperm, as it bypasses the cervix entirely. Success rates in these cases can be around 10% to 15%.
Endometriosis:
Success rates for women with mild endometriosis are around 5% to 10% per cycle.
Ovulatory Disorders
Women with ovulatory disorders who use fertility medications in conjunction with IUI often have improved success rates, especially if ovulation is successfully induced.
Artificial Insemination Statistics for Specific Conditions
Intrauterine Insemination (IUI) success rates vary depending on the underlying cause of infertility.
Here’s a breakdown:
- Unexplained Infertility: 10-20% success rate per cycle
- Mild Male Factor Infertility: 5-15% success rate per cycle
- Ovulatory Disorder (with medication): 15-25% success rate per cycle
- Endometriosis: 5-10% success rate per cycle
- Cervical Factor: 10-15% success rate per cycle
IUI success rate with fertility drugs
The IUI chances of success with medications, the success rate can be around 15% to 25% per cycle. Using fertility drugs like Clomiphene Citrate, Letrozole, or gonadotropins to induce ovulation can significantly increase the chances of success.
IUI success rates without fertility drugs
The IUI Chance of Success Without Fertility Drugs is 5% to 10% per cycle.
What is the IUI success rate per multiple cycles?
The success rate after multiple cycles can reach up to 60%. The chance of getting pregnant with IUI often increases with multiple IUI cycles. Many fertility specialists recommend trying 3 to 6 cycles before considering more advanced treatments like IVF.
Other Considerations
- The quality of the sperm used in IUI plays a crucial role. Higher sperm motility and count typically lead to better success rates.
- The precise timing of the IUI procedure with ovulation is critical. Success rates are highest when IUI is performed within 24-36 hours after the trigger shot or the natural LH surge.
- The expertise and experience of the fertility clinic and the staff performing the IUI can also influence the success rate.
Summary
The success rate of IUI varies widely based on factors such as age, the underlying cause of infertility, the use of fertility medications, and the number of cycles attempted. On average, the per-cycle success rate ranges from 10% to 20%, with higher rates for younger women and those using fertility medications. Cumulative success rates can reach up to 60% after multiple cycles. Understanding these factors can help couples set realistic expectations and make informed decisions about their fertility treatment.